Gut
Health,

Meet Biome.

A daily synbiotic formula with clinically studied strains, prebiotic support, and protected delivery to help your digestion feel more balanced and steady.†

Digestive discomfort, irregularity, and microbiome imbalance are common—but they don’t have to be your norm.

  • Subtle improvements in comfort and bloating
  • Beneficial bacteria begin colonizing
  • Early signs of smoother post-meal digestion
  • Reduced bloating and more predictable regularity
  • Digestion feels more consistent throughout the day
  • Early support for the gut-brain connection as the microbiome begins to stabilize
  • Smoother digestion and improved overall comfort
  • More reliable digestive rhythm
  • A calmer gut supports a calmer internal environment, reflecting early gut-brain harmony
  • Microbial diversity becomes more established
  • Digestive comfort feels more reliable day after day
  • A balanced gut environment supports clearer, steadier overall well-being through the gut-brain axis

Engineered to Survive

MAKTREK® Bi-Pass Technology for improved survival through stomach acid

A daily synbiotic formula

Includes prebiotic support for colonization

The top researched strains

Clinically studied probiotic strains: La-14, Bl-04, Lp-115, and Lpc-37

No overloaded blends

Clean, intentional formulation with no unnecessary additives

Biome Others
Clinically studied strains ⬤ Often generic or unspecified
Protected delivery system ⬤ Basic capsules, low survival through stomach acid
Includes prebiotics ⬤ Usually not included
No refrigeration required ⬤ Often requires refrigeration
Third-party tested ⬤ Rare or not disclosed

MAKTREK® Bi-Pass Technology is a natural marine polysaccharide system that helps shield probiotics through the stomach acid, improving the amount that reach the intestines alive.

A targeted dose of 40 billion CFU from four clinically studied strains, each selected for their proven digestive and immune support.

Lactobacillus acidophilus (La-14)
Supports digestion, healthy nutrient absorption, and microbial balance in the small intestine.

Bifidobacterium lactis (Bl-04)
Promotes digestive comfort, supports regularity, and plays a key role in the gut–immune connection.

Lactobacillus plantarum (Lp-115)
Helps reinforce the gut barrier, supports balanced inflammation, and contributes to comfortable digestion.

Lactobacillus paracasei (Lpc-37)
Supports immune health and contributes to a stable, resilient gut environment.

Fructooligosaccharides (FOS) are a complementary prebiotic that feeds beneficial bacteria, helping them colonize and persist in the microbiome.

Biome Ingredients:

Combination of Probiotic Bacteria: MAKTREK® (Bi-Pass Technology), Lactobacillus Acidophilus, Bifidobacterium Lactis, Lactobacillus Plantarum, Lactobacillus Paracasei, Marine Polysaccharide Complex, Fructooligosaccharide, Hypromellose (vegetable capsule), Rice maltodextrin, L-Leucine.

‎

Why gut health matters

Your gut is more than just a digestion center—it's a complex system that affects immunity, energy, inflammation, and even cognitive function. But supporting it takes more than just throwing bacteria at the problem. It requires a blend of the right strains, delivered effectively, and supported by the right environment.

Biome was built to do exactly that.

The formula, decoded

Lactobacillus acidophilus (La-14)

A well-characterized strain that supports digestion and nutrient absorption, helps maintain balanced gut flora in the small intestine, and contributes to healthy, regular bowel movements.

Bifidobacterium lactis (Bl-04)

A highly researched strain known for supporting immune modulation, promoting digestive comfort, aiding lactose digestion, and helping maintain regularity. Often studied for its role in the gut–immune axis.

Lactobacillus plantarum (Lp-115)

A resilient strain capable of surviving stomach acidity. Promotes gut barrier integrity, supports healthy inflammatory balance in the digestive tract, and helps ease occasional bloating or discomfort.

Lactobacillus paracasei (Lpc-37)

Supports overall gut balance by reinforcing the gut lining, promoting resilience against disruptive microbes, and contributing to healthy immune responses. Often referenced in studies on allergies and immune regulation.

Feeding the foundation

Probiotics are only part of the equation. To function optimally, they require the right environment—and more importantly, the right fuel. That’s where prebiotics come in.

Prebiotics are non-digestible fibers that selectively stimulate the growth and activity of beneficial gut bacteria. Unlike probiotics, which are live organisms introduced into the system, prebiotics act as substrates—feeding the native microbiota as well as any supplemental strains introduced through Biome.

Biome includes prebiotic components to support both colonization and persistence of its four primary strains. Specifically, it contains inulin-type fructans, which have been shown in research to enhance the growth of Bifidobacterium and Lactobacillus species—two of the dominant genera in this formula.

This prebiotic inclusion helps accomplish several key functions:

  • Improved survivability and colonization of the included strains
  • Selective fermentation, favoring beneficial bacteria over potentially pathogenic organisms
  • Support for short-chain fatty acid (SCFA) production, such as butyrate, which contributes to gut barrier integrity and systemic immune modulation
  • Promotion of microbial diversity, which is increasingly linked to long-term gut and metabolic health

By including both probiotics and prebiotics, Biome functions as a synbiotic—a formulation that combines both microbial strains and their preferred fuel source. This dual strategy enhances not only the initial delivery but also the sustainability of microbial balance within the gut over time.

The delivery system

Transporting probiotic strains safely through the acidic environment of the stomach is one of the greatest challenges in formulation. MAKTREK® is a proprietary, marine-derived coating technology designed to enhance the survivability of live bacteria, helping more active cultures arrive intact in the gut—where they can do their work.

While its full technical design is proprietary, MAKTREK® is built on established principles of gastro-resistant encapsulation. The system is engineered to protect live cultures during stomach transit and support their stability and persistence once they reach the intestines.

¹ A comprehensive review of probiotics and human health-current prospective and applications

² The Role of Prebiotics in Modulating Gut Microbiota: Implications for Human Health

Vegan

Gluten-Tested

Nut-Tested

No Refrigeration Required

Dairy-Tested

Third-Party Tested

Soy-Tested

Made In USA

Backed By Our Standards

30-Day Worry-Free Guarantee

If our products aren’t the right fit for you, let us know within 30 days for a full refund—no questions asked.

Flexible Subscriptions

Start, pause, skip, or cancel whenever you need. Adjust your delivery schedule to match your routine, not the other way around.

Free Shipping on All Orders

Every order ships free with dependable, trackable delivery.

Support When You Need It

Questions about your order or your routine? We're here to help—every step of the way.

Ready to Begin?

Biome

Biome

$44.00
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Biome
  • Biome
  • Biome
Biome

Biome

A clinically studied, 40 billion CFU probiotic + prebiotic for everyday gut balance, digestive comfort, and whole-body support.†

$44.00

30-day supply

$44.00 USD
$39.60 USD

Auto-renews, skip or cancel anytime.

To add to cart, go to the product page and select a purchase option

30-day worry-free guarantee. Free US shipping.

Frequently Asked Questions

Take 2 capsules once daily, ideally on an empty stomach. If you find it more comfortable to take it with food, that’s perfectly fine as well. What's important is that you take them consistently.

Your gut is home to trillions of microbes that influence digestion, energy, immunity, and everyday comfort. Biome supports that ecosystem with 40 billion CFU from four clinically studied strains—all chosen to help reinforce gut balance, support nutrient absorption, and keep things running smoothly. It’s a simple daily step that supports a healthier gut environment.

Think of Biome as support for the “neighborhood” living inside your gut. It introduces strains that help with digestion, regularity, gut barrier integrity, and healthy microbial balance—all working together to keep your system feeling steady and resilient.

Biome plays well with most supplements. If you take prescription medications or have a medical condition, we always recommend checking with your healthcare provider before adding something new to your routine.

Not yet. We currently ship within the US only.